In this paper, an innovative biodegradable, biocompatible and implantable piezoelectric composite is proposed. Bacterial cellulose (BC) was functionalized by adding piezoelectric ZnO nanoparticles (NPs) obtaining free-standing piezoelectric nanocomposites (BC@ZnO). BC was obtained as a product of the fermentation process by Gluconacetobacter xylinum using food wastes. Composites with 5 to 40 wt% of ZnO in the BC matrix were prepared by stirring fibrillated BC pulp in a ZnO suspension, followed by vacuum filtration. The joint results coming from X-ray diffraction, scanning electron microscopy and Fourier-transform infrared spectroscopy analyses demonstrate the efficacy of the proposed synthesis route to achieve BC@ZnO nanocomposite films. The paper discusses extensively the impact of ZnO content on piezoelectric response by using Piezoresponse Force Microscopy for the first time for BC@ZnO …