Bacterial cellulose (BC) is a promising, green, biocompatible polysaccharide that can be used to produce flexible, eco-friendly electronic devices. However, its high surface roughness and porosity can hinder uniform deposition of the material, which compromises device fabrication and performance. These limitations have been addressed by combining mechanical treatments with the application of natural polymeric coatings. Additionally, a chemical cleaning process is introduced to remove residual compounds such as NaOH, chalk, and CaCO3, which are typically used during BC sheet processing. The effectiveness of the treatments was evaluated by using FT-IR spectroscopy, optical microscopy, and SEM/EDX analysis. Finally, inkjet printing is employed to assess the enhanced printability of the treated BC, showcasing its viability as a substrate for printing electronic components.