KLVFF peptide functionalization of graphene oxide as suitable Aβ biomarker detection platform

Publication date: 20 Set 2024

conference-paperSource: OPENALEXOpenAlex type: conference-paperOpen Access
Authors: Rita Turnaturi, Giuseppina Sabatino, Giuseppe Di Natale, Giuseppe Nocito, Angela Scala, Viviana Scuderi, Simona Filice, Antonino Mazzaglia, Silvia Scalese, Giuseppe Pappalardo

KLVFF peptide functionalization of graphene oxide as suitable Aβ biomarker detection platformHowever, the invasiveness and the difficult access to routine diagnosis, due to high costs of these tools, represent some challenges that need to be overcome.In this scenario, KLVFF (H 2 N-Lys-Leu-Val-Phe-Phe-COOH, Aβ (16-20)), a peptide fragment deputed to interact with the homologous region of full-length Aβ(1-40) or Aβ (1-42), was selected as molecular recognition element of the selected Aβ biomarkers.

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